Activity of all the neurons recorded in the mouse brain, whilst the animal does a correct trial in the IBL-task

What do we study ?

Adaptive behavior requires processing sensory information with focused attention, reaching decisions, acting, and learning from the results of those actions. These require the brain to combine a vast array of information from prior experience, current sensory stimuli, and internal and environmental contexts. These computations involve dynamic interactions between millions of neurons within local circuits and across many brain regions.

How is our study conducted ?

We conduct our study on mice trained to do a standardized task, that prompts adaptive behavior. We recorded the signals from multiple single neurons using Neuropixels probes inserted into one hemisphere of the mouse brain. We also recorded the mouse motion using cameras, and various signals from other sensors.

For a comprehensive view, please explore the data, or read the article detailing the task and the article detailing our standardized recording methods.

The data was collected in 12 different laboratories across the globe.

What is our aim ?

We want to provide a dataset containing the activity of thousands single neurons in a volume spanning the whole hemisphere of the mouse brain.

How much data do we have ?

We recorded 621,733 neurons (out of which 75,708 are considered to be neurons) in 139 mice performing the task, by doing 699 insertions with Neuropixels probes.

Contributors

Data collection

  • Julius Benson, Center for Neural Science, New York University, New York, NY, USA
  • Joana Catarino, Champalimaud Center for the Unknown, Lisboa, Portugal
  • Fei Hu, Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA
  • Anup Khanal, Department of Neurobiology, University of California, Los Angeles, CA, USA
  • Christopher Krasniak, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
  • Petrina Lau, Wolfson Institute of Biomedical Research, University College London, London, United Kingdom
  • Guido Meijer, Champalimaud Center for the Unknown, Lisboa, Portugal
  • Nathaniel Miska, Sainsbury-Wellcome Centre, University College London, London, UK
  • Jean-Paul Noel, Center for Neural Science, New York University, New York, NY, USA
  • Noam Roth, Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland
  • Karolina Socha, Institute of Opthalmology, University College London, London, United Kingdom
  • Anne Urai, Cognitive Psychology Unit, Institute of Psychology and Leiden Institute for Brain and Cognition, Leiden University, Leiden, Netherlands

Website development, supervision

  • Daniel Birman, Department of Biological Structure, University of Washington, Seattle, WA, USA
  • Gaelle Chapuis, Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland
  • Mayo Faulkner, Institute of Neurology, University College London, London, UK
  • Cyrille Rossant, Institute of Neurology, University College London, London, UK